Biovance Amniotic Membrane and Interfyl Connective Tissue Matrix for Foot and Ankle Procedures

Kirk A. McCullough, MD (Leawood, KS), discusses the benefits and applications of augmentation with placental tissue products, including Biovance^® amniotic membrane and Interfyl^® connective tissue matrix (CTM), for foot and ankle orthopedic procedures. Biovance membrane serves as a natural scaffold that supports a high level of fibroblast and keratinocyte attachment,¹ or as a barrier membrane during the wound regeneration process to support tissue growth.² Interfyl CTM provides a native extracellular matrix for cell attachment.³

Biovance and Interfyl are trademarks of Celularity Inc.

^References

^{1. Bhatia M, Pereira M, Rana H, et al. The mechanism of cell interaction and response on decellularized human amniotic membrane: implications in wound healing. Wounds. 2007;19(8):207-217.}

^{2. Niknejad H, Peirovl H, Jorjani M, et al. Properties of the amniotic membrane for potential use in tissue engineering. Eur Cell Mater. 2008;15:88-99.}

^{3. Pashuck ET, Mao Y, Kim K, John K, Smiell J, Bhatia MB. A human placenta-derived decellularized connective tissue matrix (CTM) supports cellular functions involved in wound healing processes. Paper presented at: Symposium on Advanced Wound Care; October 7-9, 2016. Las Vegas, NV.}